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- 2. GASTRITIS Classification of gastritis: 1. Acute (erosive/hemorrhagic) gastritis 2. Chronic (non-erosive) 3. Specific forms of gastritis
- 3. Morphological forms of acute gastritis: 1. Catarrhal (simple) - edema, hyperemia, lympho- and leucocytes infiltration of
- 4. MORPHOLOGICAL FEATURES Types of gastric epithelium damages: 1. localized - involving the acid-secreting mucosa of the
- 5. Clinical Course Depending on the severity of the anatomic changes, acute gastritis may be: asymptomatic may
- 6. CHRONIC (NON-EROSIVE) GASTRITIS Chronic gastritis is characterized by the absence of visible mucosal erosions and by
- 7. Main variants of chronic gastritis: I. Autoimmune chronic gastritis (Type A) it is related to pernicious
- 8. Main variants of chronic gastritis: III. Chronic atrophic pan-gastritis (Type B) – it is characterised by:
- 9. MORPHOLOGY 1. The inflammatory changes may be limited to the superficial zone or may extend throughout
- 10. STRESS ULCERS Reasons of development: Severe trauma including major surgical procedures, serious sepsis, or grave illness
- 11. MORPHOLOGY Macroscopically, stress ulcers are small, round to ovoid, sometimes irregular, mucosal defects that initially involve
- 12. PEPTIC ULCER A peptic ulcer can be defined as ”a hole in the mucosa” of any
- 13. Predisposition factors of ulcer formation 1. There are hints of genetic susceptibility to duodenal ulcers (DU)
- 14. MORPHOLOGY All peptic ulcers are usually: round form - 2 to 4cm in diameter sharply punched
- 15. The histological appearance varies according to activity, chronicity and degree of healing. During the active phase,
- 16. COMPLICATIONS OF PEPTIC ULCER DISEASE I. Ulcer-destructive: 1. Bleeding - Occurs in 25 > 33% of
- 17. COMPLICATIONS OF PEPTIC ULCER DISEASE II. Inflammatory: 1. Perigastritis and/or periduodenitis 2. Phlegmon of stomach III.
- 18. TUMORS I Mesenchymal neoplasms: 1. Bening - stromal cell tumors, leiomyomas, leiomyoblastomas, neurofibromas, and lipomas 2.
- 19. GASTRIC CARCINOMA Morphologic types: 1. intestinal - arise from gastric mucous cells that have undergone metaplasia
- 20. MORPHOLOGY 1. Early gastric carcinoma (EGC) constitutes a lesion confined to the mucosa and sub-mucosa, regardless
- 21. MORPHOLOGY 2. Advanced gastric carcinoma (AGC) is a neoplasm that has extended below the sub-mucosa, into
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