Rework topic - 5 - schistosomes

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Schistosomes Schistosoma is a genus of trematodes, commonly known as blood

Schistosomes

Schistosoma is a genus of trematodes, commonly known as blood flukes.

They are parasitic flatworms responsible for a highly significant group of infections in humans termed schistosomiasis, which is considered by the World Health Organization as the second-most socioeconomically devastating parasitic disease (after malaria), with hundreds of millions infected worldwide
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Scientific classification

Scientific classification

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Geographical distribution Africa, Brazil, Cambodia, the Caribbean, China, Corsica, Indonesia, Laos,

Geographical distribution

Africa, Brazil, Cambodia, the Caribbean, China, Corsica, Indonesia, Laos,

the Middle East, the Philippines, Suriname, and Venezuela.[22] There had been no cases in Europe since 1965, until an outbreak occurred on Corsica

GEOGRAPHICAL DISTRIBUTION

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TAXONOMY Mansoni group Haematobium group Mansoni group Japonicum group

TAXONOMY

Mansoni group

Haematobium group
Mansoni group
Japonicum group

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MANSONI GROUP Schistosoma mansoni is a water-borne parasite of humans, and

MANSONI GROUP

Schistosoma mansoni is a water-borne parasite of humans, and belongs

to the group of blood flukes (Schistosoma). The adult lives in the blood vessels (mesenteric veins) near the human intestine. It causes intestinal schistosomiasis (similar to S. japonicum, S. mekongi, S. guineensis, and S. intercalatum). Clinical symptoms are caused by the eggs. As the leading cause of schistosomiasis in the world, it is the most prevalent parasite in humans.

Schistosoma mansoni is a water-borne parasite of humans, and belongs to the group of blood flukes (Schistosoma). The adult lives in the blood vessels (mesenteric veins) near the human intestine. It causes intestinal schistosomiasis (similar to S. japonicum, S. mekongi, S. guineensis, and S. intercalatum). Clinical symptoms are caused by the eggs. As the leading cause of schistosomiasis in the world, it is the most prevalent parasite in humans.

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Egg The eggs are oval-shaped, measuring 115-175 µm long and 45-47

Egg
The eggs are oval-shaped, measuring 115-175 µm long and 45-47 µm wide, and

~150 µm diameter on average. They have pointed spines towards the broader base on one side, i.e. lateral spines
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DIAGNOSIS The presence of S. mansoni is detected by microscopic examination

DIAGNOSIS

The presence of S. mansoni is detected by microscopic examination

of parasite eggs in stool. A staining method called Kato-Katz technique is used for stool examination. It involves methylene blue-stained cellophane soaked in glycerine or glass slides.] A bit costlier technique called formalin-ether concentration technique (FECT) is often used in combination with the direct faecal smear for higher accuracy. Serological and immunological tests are also available.
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HAEMATOBIUM GROUP HVS Schistosoma haematobium (urinary blood fluke) is a species

HAEMATOBIUM GROUP

HVS

Schistosoma haematobium (urinary blood fluke) is a species of digenetic

trematode, belonging to a group (genus) of blood flukes (Schistosoma). It is found in Africa and the Middle East. It is the major agent of schistosomiasis, the most prevalent parasitic infection in humans
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EGG

EGG

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DIAGNOSIS Traditionally, diagnoses has been made by examination of the urine

DIAGNOSIS

Traditionally, diagnoses has been made by examination of the urine for

eggs. In chronic infections, or if eggs are difficult to find, an intradermal injection of schistosome antigen to form a wheal is effective in determining infection. Alternatively diagnosis can be made by complement fixation tests.[28] As of 2012, commercial blood tests included ELISA and an Indirect immunofluorescence test, but these have low sensitivity ranging from 21% to 71%
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JAPONICUM GROUP cies of wild mammals, including 9 carnivores, 16 rodents,

JAPONICUM GROUP

cies of wild mammals, including 9 carnivores, 16 rodents, one

primate (Human), two insectivores and three artiodactyls and therefore it can be considered a true zoonosis.

Schistosoma japonicum is an important parasite and one of the major infectious agents of schistosomiasis.This parasite has a very wide host range, infecting at least 31 species of wild mammals, including 9 carnivores, 16 rodents, one primate (Human), two insectivores and three artiodactyls and therefore it can be considered a true zoonosis.

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EGG

EGG

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DIAGNOSIS Microscopic identification of eggs in stool or urine is the

DIAGNOSIS

Microscopic identification of eggs in stool or urine is the most

practical method for diagnosis. Stool examination should be performed when infection with S. mansoni or S. japonicum is suspected, and urine examination should be performed if S. haematobium is suspected. Eggs can be present in the stool in infections with all Schistosoma species.
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