Рибозимы в регенеративной медицине

Слайд 2

Рибозимы - это молекулы РНК с каталитическими свойствами - ферментов, состоящие

Рибозимы - это молекулы РНК с каталитическими свойствами - ферментов, состоящие

из нуклеиновых кислот.

T.M. Picknett, S. Brenner, in Encyclopedia of Genetics, 2009

Слайд 3

Twister Ribozyme Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes Ki-Young Lee and Bong-Jin Lee

Twister Ribozyme

Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes
Ki-Young Lee and

Bong-Jin Lee
Слайд 4

Twister Sister Ribozyme Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes Ki-Young Lee and Bong-Jin Lee

Twister Sister Ribozyme

Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes
Ki-Young Lee

and Bong-Jin Lee
Слайд 5

Pistol Ribozyme Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes Ki-Young Lee and Bong-Jin Lee

Pistol Ribozyme

Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes
Ki-Young Lee

and Bong-Jin Lee
Слайд 6

GW26-e2354 R65 Ribozyme Gene Attenuates ox-LDL Induced Apoptosis in HASMCs Conclusions

GW26-e2354 R65 Ribozyme Gene Attenuates ox-LDL Induced Apoptosis in HASMCs
Conclusions
Over-expression of

R65 ribozyme gene inhibited the activity of the NF-κB pathway and reduced the apoptosis of HASMCs.
Слайд 7

Влияние на добровольное употребление алкоголя Hairpin Ribozyme Genes Curtail Alcohol Drinking:

Влияние на добровольное употребление алкоголя

Hairpin Ribozyme Genes Curtail Alcohol Drinking: from

Rational Design to in vivo Effects in the Rat
Слайд 8

Влияние на уровень ацетальдегида в крови Hairpin Ribozyme Genes Curtail Alcohol

Влияние на уровень ацетальдегида в крови

Hairpin Ribozyme Genes Curtail Alcohol Drinking:

from Rational Design to in vivo Effects in the Rat