Initiation of translation in prokaryotes: initiation factors, initiator codons, 3'end of RNA small ribosomal subunit
Содержание
- 2. In molecular biology and genetic, translation is the process in which ribosomes in a cell's cytoplasm
- 3. Translation proceeds in three phases: Initiation: The ribosome assembles around the target mRNA. The first tRNA
- 4. In bacteria, translation occurs in the cytoplasm, where the large and small subunits of the ribosome
- 5. A number of antibiotics act by inhibiting translation. These include anisomycin, cycloheximide, chloramphenicol, tetracycline, streptomycin, erythromycin,
- 6. Translation initiation: Initiation factors Prokaryotes require the use of three initiation factors: IF1, IF2, and IF3,
- 7. Translation initiation: Initiation factors IF2 binds to an initiator tRNA and controls the entry of tRNA
- 8. Translation initiation: Initiation factors IF3 is not universally found in all bacterial species but in E.
- 10. The fact that cells typically contain many ribosomes reflects the central importance of protein synthesis in
- 11. * Each ribosome contains one copy of the rRNAs and one copy of each of the
- 12. A noteworthy feature of ribosomes is that they can be formed in vitro by self-assembly of
- 13. Ribosome: rRNA -rRNAs are much more than structural components of ribosome directly responsible for the key
- 14. Ribosome: 16S rRNA 1)A site: binding site for aminoacyl-tRNA 2)P site: binding site for peptidyl-tRNA 3)E
- 15. Ribosome: 16S rRNA (Zwieb & Brimacombe I979)
- 16. Ribosome: 16S rRNA The arrangement of the 16S rRNA creates a 5' domain, central domain, 3'
- 17. Ribosome: 16S rRNA The 3' major domain contains 15 helical elements and composes the head. The
- 19. First, the small subunit associates with the mRNAby base-pairing interaction between RBS and 16S rRNA -the
- 20. Ribosome: 3’ end of 16 s rRNA Unique localization of the 3' end of the RNA
- 21. Ribosome: 3’ end of 16 s rRNA Cross-linking studies have shown that the nucleic acid-binding domain
- 22. Antibiotics affecting 16S rRNA Colicin E3 (protein antibiotic from E.coli) makes a single cut in the
- 23. Shine-Dalgarno sequence
- 24. The Shine-Dalgarno (SD) sequence is a ribosomal binding site in bacterial and archaeal messenger RNA, generally
- 27. several examples of the Shine-Dalgarno sequence
- 28. REFERENCE The Cell: A Molecular Approach. 2nd edition.Cooper GM. Sunderland (MA): Sinauer Associates; 2000. Watson J
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