Dialog+ SW 9.xx HDF Online. Technical Support International

Содержание

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HDF Online Upgrade to HDF Online not possible Downgrade to standard

HDF Online

Upgrade to HDF Online not possible
Downgrade to standard

machine not possible
All filters are always in use
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What does HDF Online offer? A safe procedure with a combination

What does HDF Online offer?
A safe procedure with a combination of

HD and HF.
High efficiency with diffusion and convection.
Online production of substitution solution.
Replacing saline for priming and disconnecting the patient.
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Combines two dialysis technics, Hemodialysis and Hemofiltration High clearance of small

Combines two dialysis technics,
Hemodialysis and Hemofiltration
High clearance of small molecules through

diffusion
High clearance of middle molecules through convection

mmHg

B

B

D

high-flux

Diffusion + Convection
Hemodiafiltration

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HF B HD B D B D HDF mmHg B mmHg

HF

B

HD

B

D

B

D

HDF

mmHg

B

mmHg

D

B

D

low-flux

high-flux

high-flux

Diffusion

Convection Adsorption

Diffusion/Convection Adsorption
Types of Therapies

with HDF Online
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HDF Online Concept PV PA BLD high-flux PBE Preadapter BPA OSP Substitution port Postdilution Predilution

HDF Online Concept

PV

PA

BLD

high-flux

PBE

Preadapter

BPA

OSP

Substitution port

Postdilution

Predilution

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AAMI = American Association for the Advancement of Medical Instrumentation Ph.

AAMI = American Association for the Advancement of Medical Instrumentation
Ph. Eur.

= European Pharmakopoe
CFU = Colony Forming Units
EU = Endotoxin Units

Microbiological Requirements

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HDF Online Icon

HDF Online Icon

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HDF-Online Message: “Ratio gross UF rate/blood flow“ Start therapy in HD

HDF-Online Message: “Ratio gross UF rate/blood flow“

Start therapy in HD

Mode
First reach correct blood flow
Change to HDF Mode

Supresses platelet activation
Lowers protein adsorption
Reduces hemolysis and clotting

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Increase of TMP at start of HDF dialysis hollow fibre diffusive

Increase of TMP at start of HDF dialysis

hollow fibre

diffusive layer

A

high TMP in the beginning of therapy causes proteins to block the pores
The efficiency of the therapy is reduced
Blocking of the pores reduces the surface area
Even in UF Min the machine has a high Ultrafiltration
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Example for post-dilution: body weight 81 kg weight loss 3 kg

Example for post-dilution:
body weight 81 kg
weight loss 3 kg
treatment time 5 h

Substituition volume 27

l/h
UF rate 6 l/h (100 ml/min)
nett UF 30 l
total UF 3 l
blood flow 300 ml/min

HDF-Online Message: “Ratio gross UF rate/blood flow“

In postdilution the ratio of total UF/blood flow can be max. 25-30%
In postdilution 30-40 L substitution volume
total substitution volume 1/3 of patient‘s body weight
In predilution 70-100 L substitution volume

30% of 81 = 27 l
27 l + 3 l weight loss = 30 l
30 l : 5 h = 6 l/h
6 l/h : 60 min = 100 ml/min
blood flow 350 ml/min

Example for a patient with 81 kg

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Hardware Components Substitution ports for infusing of the substitution fluid pre-

Hardware Components

Substitution ports for infusing of the substitution fluid pre-

or postdilution
Automatic priming of the tubing set with substitution fluid
2 DF filters to ensure clean substitution fluid
replaceable every 150 treatments or 900 hours
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HDF Online – Blood Side Preparation Inlet Outlet SAD RDV PV

HDF Online – Blood Side Preparation

Inlet

Outlet

SAD
RDV

PV PA PBE


BPA HP

OSP (Online

Substitution Pump)

SAKV

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HDF Online Therapy SAD RDV PV PA PBE BPA HP Inlet

HDF Online Therapy

SAD
RDV

PV PA PBE


BPA HP

Inlet

Outlet

OSP (Online Substitution

Pump)

SAKV

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HDF Online Reinfusion SAD RDV PV PA PBE BPA HP Inlet

HDF Online Reinfusion

SAD
RDV

PV PA PBE

BPA HP

Inlet

Outlet

OSP (Online Substitution Pump)

SAKV

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Balance Chamber Principle Phase 1 Inlet Flow Pump Balance Chamber Air

Balance Chamber Principle Phase 1

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow

Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

DDE

FPE

RVDA

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Inlet Flow Pump Balance Chamber Air Separator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

Balance

Chamber Principle Phase 1

DDE

FPE

RVDA

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Inlet Flow Pump Balance Chamber Air Separator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

Balance

Chamber Principle Phase 1

DDE

RVDA

FPE

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Inlet Flow Pump Balance Chamber Air Separator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

FPE

Balance

Chamber Principle Phase 1

DDE

RVDA

PDA

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Inlet Flow Pump Balance Chamber Air Separator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

Balance

Chamber Principle Phase 1

FPE

DDE

RVDA

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Inlet Flow Pump Balance Chamber Air Seperator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Seperator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

Balance

Chamber Principle Phase 2

DDE

RVDA

FPE

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Inlet Flow Pump Balance Chamber Air Separator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

Balance

Chamber Principle Phase 2

DDE

RVDA

FPE

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Inlet Flow Pump Balance Chamber Air Separator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

Balance

Chamber Principle Phase 2

DDE

RVDA

FPE

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Inlet Flow Pump Balance Chamber Air Separator LA Outlet Flow Pump

Inlet Flow Pump

Balance Chamber

Air Separator LA

Outlet Flow Pump FPA

Ultrafiltration Pump UFP

BLD

PDA

Balance

Chamber Principle Phase 2

DDE

FPE

RVDA

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Producing Substitution Fluid Balancing DF-Filter HDF Filter OSP FPE FPA UFP Postdilution Predilution

Producing Substitution Fluid

Balancing

DF-Filter

HDF Filter

OSP

FPE

FPA

UFP

Postdilution

Predilution

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DF-Filter OSP HDF Online Balancing Chamber 600ml/min 600ml/min 520ml/min 600ml/min +

DF-Filter

OSP

HDF Online Balancing Chamber

600ml/min

600ml/min

520ml/min

600ml/min
+ Patient UFP

80ml/min

80ml/min

80ml/min
+ Patient UFP

+

Patient UFP

600ml/min

FPE

FPA

Balancing

Postdilution

Predilution

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HDF Online – Dialysate Distribution in the Filter QB 300 ml/min

HDF Online – Dialysate Distribution in the Filter

QB 300 ml/min

QB 290

ml/min

QUF 90 ml/min

QD 600 ml/min

QD 520 ml/min

QS 80 ml/min

QB 210 ml/min

QD 610 ml/min

DF Filter

HDF Filter

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Infusion Bolus – Patient Connection and Disconnection DF Filter OSP For

Infusion Bolus – Patient Connection and Disconnection

DF Filter

OSP

For infusion the balancing

chamber and
UF pump are stopped

Free Flow Mode

Postdilution

Predilution

FPE

FPA

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DF Filter OSP FPE FPA UFP HDF Online – Hydraulics HFB

DF Filter

OSP

FPE

FPA

UFP

HDF Online – Hydraulics

HFB

VDE

VDA

VBP

VSAA

VSAE

VDFF

VLA

VSB

DDE

RVDA

RVFPE

RVFPA

VBE

Postdilution

Predilution

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HDF Online – Hydraulics 1 Hydrophobe filter with adapter 2 Valve 3/2 way

HDF Online – Hydraulics

1 Hydrophobe filter with adapter
2 Valve 3/2 way

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Rinsing DF Filter HDF Filter OSP ~ 1 Minute HDF Online

Rinsing

DF Filter

HDF Filter

OSP

~ 1 Minute

HDF Online – Rinsing after a DF

Problem
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HDF Online – Electronics Tests in TSM

HDF Online – Electronics

Tests in TSM

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HDF Online – Filter Testing DF, HDF Filter Tests DF Filter

HDF Online – Filter Testing

DF, HDF Filter Tests

DF Filter

PDA

DDE

RVDA

RVFPA

FPA

UFP

VDFF

VSB

VBP

VDE

VDA

VSAE

VSAA

VLA

VBE

FPE

RVFPE

Manometer

HFB

The hydraulic circuit

is tested with
VDFF, VSB, VSAE + VSAA

H2O

FVD

FSU

FBK1

FBK2

500 mbar

400 mbar

650 - 750 mbar

500 mbar

1000 rpm

500 rpm

Free Flow Mode

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HDF Online – Filter Test Air is flushed from the DF-Filter

HDF Online – Filter Test

Air is flushed from the DF-Filter

DF Filter

PDA

DDE

RVDA

RVFPA

FPA

UFP

VDFF

VSB

VBP

VDE

VDA

VSAE

VSAA

VLA

VBE

FPE

RVFPE

Manometer

HFB

H2O

FVD

FSU

FBK1

FBK2

500

mbar

150 - 250 mbar

1000 rpm

500 rpm

The hydraulic circuit is tested with
VDFF, VSB, VSAE + VSAA

Free Flow Mode

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HDF Online – Filter Tests DF, HDF Filter and Port Tests

HDF Online – Filter Tests

DF, HDF Filter and Port Tests

DF Filter

HDF

Filter

PDA

DDE

RVDA

RVFPA

FPA

UFP

VDFF

VSB

VBP

VDE

VDA

VSAE

VSAA

VLA

VBE

FPE

RVFPE

Manometer

HFB

H2O

FVD

FSU

FBK1

FBK2

500 mbar

350 - 450 mbar

1000 rpm

500 rpm

The hydraulic circuit is tested with
VDFF, VSB, VSAE + VSAA

Free Flow Mode

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HDF Online – Filter Test DF, HDF Filter and Port Tests

HDF Online – Filter Test

DF, HDF Filter and Port Tests

H2O

FVD

DF Filter

PDA

DDE

RVDA

RVFPA

FPA

UFP

VDFF

VSB

VBP

VDE

VDA

VSAE

VSAA

VLA

VBE

FPE

RVFPE

Manometer

HFB

FSU

FBK1

FBK2

500

mbar

400 mbar

-100 mbar

500 mbar

0 rpm

500 rpm

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Calibration RVDA and RVFPE RVDA 500 mbar RVFPE 1.3 bar Measuring

Calibration RVDA and RVFPE

RVDA 500 mbar

RVFPE 1.3 bar

Measuring point for both

calibrations:
flow 500ml/min and temperature 37 °C

without clamp for RVDA adjustment
with clamp the tube next to the FBK2 for RVFPE adjustment

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Calibration of RVFPA During the calibration pay attention to the following:

Calibration of RVFPA

During the calibration pay attention to the following:
Both dialyser

couplings should be in a water filled container
The DF filters must be decalcified and free of air
Low level test 1.20 Settings: flow 500ml/min, temperature 37 °C
Clamp the tube next to the FBK2

RVFPA 1.3 bar

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Calibration of DDE During the calibration pay attention to the following:

Calibration of DDE

During the calibration pay attention to the following:
Both

dialyser couplings should be in a water filled container
The DF filters must be decalcified and free of air
Low level test 1.20 Settings: flow 500ml/min, temperature 37 °C

DDE 400 mbar

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Change after 150 Treatments or 900 Hours Follow the correct procedure

Change after 150 Treatments or 900 Hours

Follow the correct procedure
Chemical disinfection

with Tiutol® KF with the old filter
Empty the filter
Test for residual disinfectant
Change the filter
Reset the counter
Fill in the rinsing mode for 5 minutes
Citric heat disinfection
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Maintenance Kit

Maintenance Kit