Биохимия легких

Сентябрь 2, 2022

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Биохимия легких

Содержание

2. Введение Основные функции легких Продукция различных веществ (сурфактант, слизь, коллаген), Синтез БАВ - АФК, кинины, биогенные
3. Основные функции легких Газообмен (поддержка и обеспечение аэробного энергетического обмена, детоксикации, синтеза БАВ) Регуляция КОС Экскреторная
4. No smoking!
5. No smoking!
6. Болезни легких Болезни легких обычно группируются по тому как влияют на функцию легких: Обструктивные болезни легких
7. No smoking! Some diseases are difficult to categorize because they can harm the lungs in a
8. Lung Emphysema Is a lung disease in which victims have difficulty breathing, especially when they exhale.
9. How Emphysema Affects Breathing Fresh air is carried through the airways to alveoli, contain a network
10. Symptoms of Emphysema difficulty in breathing, especially during exhalation; shortness of breath; an enlarged chest; bluish
11. Causes and Treatment of Emphysema Causes: cigarette smoking; air pollution; environmental or occupational hazards; repeated infections;
12. Smoking is Shameful!
13. Smoking is Lucky Shot!
14. Stop Smoking!
15. Smoking Kills!
16. Smoking Kills!
17. No smoking!
18. No smoking!
19. …to smoke or not to smoke?
20. Smoking Causes Cancer!
21. Smoking shortens your days!
22. Smoking makes your look fool!
23. Smoking is dangerous!
24. Smoking kills!
25. Smoking = Lung Cancer
26. Smoking steels your days!
27. Smoking Kills!
28. Респираторный дистресс синдром (болезнь гиалиновых мембран) …or respiratory distress syndrome, is a lung condition that affects
29. Респираторный дистресс синдром The term hyaline membrane refers to the clear, glassy membranes found in the
30. Surfactant Underdeveloped lungs lack pulmonary surfactant: prevents the air sacs from collapsing. respirators and high-humidity incubators:
36. Скачать презентацию

Слайд 2

Введение
Основные функции легких
Продукция различных веществ (сурфактант, слизь, коллаген),
Синтез БАВ

- АФК, кинины, биогенные амины – серотонин, гистамин, катехоламины
Инактивация БАВ
Активация ангиотензина
АОЗ (ферментативная и не ферментативная).
Сурфактант, его продукция и контроль.

Слайд 3

Основные функции легких
Газообмен (поддержка и обеспечение аэробного энергетического обмена, детоксикации, синтеза

БАВ)
Регуляция КОС
Экскреторная – удаление СО2 и др.
Ловушка мелких тромбов
Инактивация и катаболизм БАВ
Активация БАВ
Детоксикация ксенобиотиков

Слайд 4

No smoking!

Слайд 5

No smoking!

Слайд 6

Болезни легких
Болезни легких обычно группируются по тому как влияют на функцию

легких:
Обструктивные болезни легких (эмфизема, астма, хр. бронхит) Obstructive lung diseases, such as emphysema, asthma, and chronic bronchitis, cause the airways to become partly blocked or narrower, making it more difficult for air to move through them.
Cigarette smoking and air pollution are major causes of these diseases.
Restrictive lung diseases make it harder for the respiratory system to expand. They can cause a stiffening of the lung or chest wall or make the respiratory muscles unable to respond to nerve signals from the brain.
Breathing substances such as asbestos, silica, and coal dust can cause some types of restrictive disease.
Pulmonary vascular diseases affect the circulation of blood in the lungs.
For example, in pulmonary hypertension, the small blood vessels of the lung become narrower, making it difficult for the right side of the heart to pump blood.

Слайд 7

No smoking!
Some diseases are difficult to categorize because they can harm

the lungs in a number of ways.
Some pollutants--particularly cigarette smoke--affect the cilia, causing the upward movement of mucus to slow or stop.
Smoking cigarettes is also a major cause of lung cancer. Infectious lung diseases, such as tuberculosis and pneumonia, are caused by bacteria, viruses, or other organisms.
These diseases are serious health concerns in all parts of the world.

Слайд 8

Lung Emphysema
Is a lung disease in which victims have difficulty breathing,

especially when they exhale.
Emphysema is one of the two main forms of chronic obstructive pulmonary diseases (COPD).
The other is chronic bronchitis.
Chronic obstructive pulmonary diseases are characterized by progressive narrowing of the airways.

Picture source: US Food and Drug Administration
http://64.143.176.9/library/healthguide/en-us/images/media/medical/hw/h9991437_001.jpg

Слайд 9

How Emphysema Affects Breathing
Fresh air is carried through the airways to

alveoli, contain a network of pulmonary capillaries. The gas exchange occurs.
Emphysema destroys the walls of alveoli, including the pulmonary capillaries. The lung begins to lose elasticity and becomes overinflated as more air is inhaled and trapped in the air spaces.
Thus, emphysema disrupts the flow of carbon dioxide from the body and deprives body tissues of needed oxygen.

Picture source: The New York Times
http://graphics8.nytimes.com/images/2007/08/01/health/adam/17055.jpg

Слайд 10

Symptoms of Emphysema
difficulty in breathing, especially during exhalation;
shortness of breath;

an enlarged chest;
bluish skin color
resulting from a less than normal amount of oxygen in the blood.
Emphysema victims often suffer from frequent colds and lung infections. Some also develop serious heart disease.

Слайд 11

Causes and Treatment of Emphysema
Causes:
cigarette smoking;
air pollution;
environmental or occupational

hazards;
repeated infections;
genetic factors;
α1-antitrypsine deficiency.
Macrophagal proteases can destroy the alveolar walls in emphysema victims. α1-antitrypsine control these enzymes.

Treatment.
Emphysema cannot be cured, but treatment may help reduce further lung damage.
Victims of emphysema should
avoid cigarette smoking and air pollution.
promptly treat recurrent colds and infections.
Many victims are helped by drugs, physical therapy, special breathing techniques, and by breathing oxygen-enriched air.

Слайд 12

Smoking is Shameful!

Слайд 13

Smoking is Lucky Shot!

Слайд 14

Stop Smoking!

Слайд 15

Smoking Kills!

Слайд 16

Smoking Kills!

Слайд 17

No smoking!

Слайд 18

No smoking!

Слайд 19

…to smoke or not to smoke?

Слайд 20

Smoking Causes Cancer!

Слайд 21

Smoking shortens your days!

Слайд 22

Smoking makes your look fool!

Слайд 23

Smoking is dangerous!

Слайд 24

Smoking kills!

Слайд 25

Smoking = Lung Cancer

Слайд 26

Smoking steels your days!

Слайд 27

Smoking Kills!

Слайд 28

Респираторный дистресс синдром (болезнь гиалиновых мембран)
…or respiratory distress syndrome, is a

lung condition that affects premature babies.
underdevelopment of the lungs of these infants.
The air sacs of the lungs collapse, causing rapid, difficult breathing and, in many cases, death by suffocation.
Hyaline membrane disease ranks as a major cause of death among premature infants.

Слайд 29

Респираторный дистресс синдром
The term hyaline membrane refers to the clear, glassy

membranes found in the lungs of babies that die of the disease.
Many physicians believe these membranes are produced as a reaction to lung damage caused by the strain of breathing air in an immature lung.

Слайд 30

Surfactant
Underdeveloped lungs lack pulmonary surfactant: prevents the air sacs from collapsing.

respirators and high-humidity incubators: 4-5 days of therapy, then lungs produce pulmonary surfactant.
Artificial surfactants can be given to infants soon after birth to prevent the disease.

Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid and the major constituent of pulmonary surfactant.

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Биохимия легких

Содержание

ВведениеОсновные функции легких Продукция различных веществ (сурфактант, слизь, коллаген), Синтез БАВ

Основные функции легкихГазообмен (поддержка и обеспечение аэробного энергетического обмена, детоксикации, синтеза

No smoking!

No smoking!

Болезни легкихБолезни легких обычно группируются по тому как влияют на функцию

No smoking!Some diseases are difficult to categorize because they can harm

Lung EmphysemaIs a lung disease in which victims have difficulty breathing,

How Emphysema Affects BreathingFresh air is carried through the airways to

Symptoms of Emphysema difficulty in breathing, especially during exhalation; shortness of breath;

Causes and Treatment of EmphysemaCauses:cigarette smoking; air pollution; environmental or occupational

Smoking is Shameful!

Smoking is Lucky Shot!

Stop Smoking!

Smoking Kills!

Smoking Kills!

No smoking!

No smoking!

…to smoke or not to smoke?

Smoking Causes Cancer!

Smoking shortens your days!

Smoking makes your look fool!

Smoking is dangerous!

Smoking kills!

Smoking = Lung Cancer

Smoking steels your days!

Smoking Kills!

Респираторный дистресс синдром (болезнь гиалиновых мембран)…or respiratory distress syndrome, is a

Респираторный дистресс синдромThe term hyaline membrane refers to the clear, glassy

SurfactantUnderdeveloped lungs lack pulmonary surfactant: prevents the air sacs from collapsing.

Похожие презентации

Введение
Основные функции легких
Продукция различных веществ (сурфактант, слизь, коллаген),
Синтез БАВ

Основные функции легких
Газообмен (поддержка и обеспечение аэробного энергетического обмена, детоксикации, синтеза

Болезни легких
Болезни легких обычно группируются по тому как влияют на функцию

No smoking!
Some diseases are difficult to categorize because they can harm

Lung Emphysema
Is a lung disease in which victims have difficulty breathing,

How Emphysema Affects Breathing
Fresh air is carried through the airways to

Symptoms of Emphysema
difficulty in breathing, especially during exhalation;
shortness of breath;

Causes and Treatment of Emphysema
Causes:
cigarette smoking;
air pollution;
environmental or occupational

Респираторный дистресс синдром (болезнь гиалиновых мембран)
…or respiratory distress syndrome, is a

Респираторный дистресс синдром
The term hyaline membrane refers to the clear, glassy

Surfactant
Underdeveloped lungs lack pulmonary surfactant: prevents the air sacs from collapsing.