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- 2. SARS-CoV - severe acute respiratory syndrome outbreaks in 2002 and 2003 in Guangdong Province, China. MERS-CoV
- 3. SARS has flu-like symptoms that usually begin 2 to 7 days after infection Sometimes, the time
- 4. The predominant pattern CT bilateral (64 [79%] patients) peripheral (44 [54%]) ill-defined (66 [81%]), and ground-glass
- 5. N Zhu et al. N Engl J Med 2020;382:727-733. Three adult patients presented with severe pneumonia
- 6. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30086-4/fulltext
- 7. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30086-4/fulltext
- 9. Скачать презентацию
Слайд 2
SARS-CoV - severe acute respiratory syndrome outbreaks in 2002 and 2003
SARS-CoV - severe acute respiratory syndrome outbreaks in 2002 and 2003
in Guangdong Province, China.
MERS-CoV was the pathogen responsible for severe respiratory disease outbreaks in 2012 in the Middle East.
2019-nCoV – new one
MERS-CoV was the pathogen responsible for severe respiratory disease outbreaks in 2012 in the Middle East.
2019-nCoV – new one
Слайд 3
SARS has flu-like symptoms that usually begin 2 to 7 days after infection
Sometimes,
SARS has flu-like symptoms that usually begin 2 to 7 days after infection
Sometimes,
the time between coming into contact with the virus and the start of symptoms (incubation period) can be up to 10 days.
The symptoms of SARS include:
a high temperature (fever)
extreme tiredness (fatigue)
headaches
chills
muscle pain
loss of appetite
diarrhoea
After these symptoms, the infection will begin to affect your lungs and airways (respiratory system), leading to additional symptoms, such as:
a dry cough
breathing difficulties
an increasing lack of oxygen in the blood, which can be fatal in the most severe cases
The symptoms of SARS include:
a high temperature (fever)
extreme tiredness (fatigue)
headaches
chills
muscle pain
loss of appetite
diarrhoea
After these symptoms, the infection will begin to affect your lungs and airways (respiratory system), leading to additional symptoms, such as:
a dry cough
breathing difficulties
an increasing lack of oxygen in the blood, which can be fatal in the most severe cases
https://www.nhs.uk/conditions/sars/
Слайд 4
The predominant pattern CT
bilateral (64 [79%] patients)
peripheral (44 [54%])
ill-defined
The predominant pattern CT
bilateral (64 [79%] patients)
peripheral (44 [54%])
ill-defined
(66 [81%]), and ground-glass opacification (53 [65%]),
mainly involving the right lower lobes (225 [27%] of 849 affected segments).
In group 1 (n=15), the predominant pattern was unilateral (nine [60%]) and multifocal (eight [53%]) ground-glass opacities (14 [93%]). Lesions quickly evolved to bilateral (19 [90%]), diffuse (11 [52%]) ground-glass opacity predominance (17 [81%]) in group 2 (n=21). Thereafter, the prevalence of ground-glass opacities continued to decrease (17 [57%] of 30 patients in group 3, and five [33%] of 15 in group 4), and consolidation and mixed patterns became more frequent (12 [40%] in group 3, eight [53%] in group 4).
mainly involving the right lower lobes (225 [27%] of 849 affected segments).
In group 1 (n=15), the predominant pattern was unilateral (nine [60%]) and multifocal (eight [53%]) ground-glass opacities (14 [93%]). Lesions quickly evolved to bilateral (19 [90%]), diffuse (11 [52%]) ground-glass opacity predominance (17 [81%]) in group 2 (n=21). Thereafter, the prevalence of ground-glass opacities continued to decrease (17 [57%] of 30 patients in group 3, and five [33%] of 15 in group 4), and consolidation and mixed patterns became more frequent (12 [40%] in group 3, eight [53%] in group 4).
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30086-4/fulltext
Слайд 5
N Zhu et al. N Engl J Med 2020;382:727-733.
Three adult patients
N Zhu et al. N Engl J Med 2020;382:727-733.
Three adult patients
presented with severe pneumonia and were admitted to a hospital in Wuhan on December 27, 2019.
Patient 1 - 49-year-old woman
Patient 2 was a 61-year-old man
Patient 3 was a 32-year-old man. Clinical profiles were available for Patients 1 and 2.
Patient 1 reported having no underlying chronic medical conditions but reported fever (temperature, 37°C to 38°C) and cough with chest discomfort on December 23, 2019. Four days after the onset of illness, her cough and chest discomfort worsened, but the fever was reduced; a diagnosis of pneumonia was based on computed tomographic (CT) scan. Her occupation was retailer in the seafood wholesale market.
Patient 2 initially reported fever and cough on December 20, 2019; respiratory distress developed 7 days after the onset of illness and worsened over the next 2 days (see chest radiographs, Figure 1), at which time mechanical ventilation was started. He had been a frequent visitor to the seafood wholesale market.
Patients 1 and 3 recovered and were discharged from the hospital on January 16, 2020. Patient 2 died on January 9, 2020. No biopsy specimens were obtained.
Patient 1 - 49-year-old woman
Patient 2 was a 61-year-old man
Patient 3 was a 32-year-old man. Clinical profiles were available for Patients 1 and 2.
Patient 1 reported having no underlying chronic medical conditions but reported fever (temperature, 37°C to 38°C) and cough with chest discomfort on December 23, 2019. Four days after the onset of illness, her cough and chest discomfort worsened, but the fever was reduced; a diagnosis of pneumonia was based on computed tomographic (CT) scan. Her occupation was retailer in the seafood wholesale market.
Patient 2 initially reported fever and cough on December 20, 2019; respiratory distress developed 7 days after the onset of illness and worsened over the next 2 days (see chest radiographs, Figure 1), at which time mechanical ventilation was started. He had been a frequent visitor to the seafood wholesale market.
Patients 1 and 3 recovered and were discharged from the hospital on January 16, 2020. Patient 2 died on January 9, 2020. No biopsy specimens were obtained.
Chest Radiographs.
Слайд 6
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30086-4/fulltext
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30086-4/fulltext
Слайд 7
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30086-4/fulltext
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30086-4/fulltext
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