Neurology. Spinal cord compression

Август 21, 2022

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Neurology. Spinal cord compression

Содержание

2. MOTOR NEURON DISEASE Inherited or sporadic Conditions: Amyotrophic lateral sclerosis (Lou (Gehrig disease) Progressive bulbar palsy
3. MOTOR NEURON DISEASE Symptoms: Upper mor neuron: Increase muscle tone/stiffness – spastic paralysis, overresponsive reflexes Lover
4. GUILLAIN-BARRE Acute paralytic polyneuropathy Triggered by infection : Campilobacter Jejuni Cytomegalovirus Epstain-Barr virus Symptoms: symmetrical ascending
5. GUILLAIN-BARRE Diagnosis: clinical Brighton criteria Nerve conduction studies (reduced signal) Lumbar puncture (raised protein)
6. GUILLAIN-BARRE Treatment: IV immunoglobulins Plasma exchange Supportive care VTE prophylaxis Respiratory failure: intubation and ventilation; admission
7. CHARCOT-MARIE-TOOTH Hereditary motor and sensory neuropathy of the peripheral nervous system Signs and symptoms: Muscle wasting,
8. CHARCOT-MARIE-TOOTH Diagnosis: Nerve conduction studies Nerve biopsy (onion bulb) DNA testing Treatment: no cure Occupation, physical
9. MYASTHENIA GRAVIS Autoimmune disease affecting skeletal muscles Affects young women and older men
10. MYASTHENIA GRAVIS Symptoms: Weakness neck, face, arms Eyelid drooping “Ptosis” Appearance mask-like (very sleepy look) Keep
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Слайд 2

MOTOR NEURON DISEASE
Inherited or sporadic
Conditions:
Amyotrophic lateral sclerosis (Lou (Gehrig disease)
Progressive bulbar

palsy
Primary lateral sclerosis
Spinal muscular atrophy
Post-polio syndrome

Слайд 3

MOTOR NEURON DISEASE
Symptoms:
Upper mor neuron: Increase muscle tone/stiffness – spastic paralysis,

overresponsive reflexes
Lover neuron: reduce muscle tone – flaccid paralysis; muscle wasting and twitching

Diagnosis:
clinical
neurophysiological tests and MRI of the brain and cord help differentiate from other conditions
Treatment: no cure
Riluzole (sodium channel blocker)
Cramp – Baclofen
Spasticity - Botulinum toxin
Drooling - Propantheline or Amitriptyline

Слайд 4

GUILLAIN-BARRE
Acute paralytic polyneuropathy
Triggered by infection :
Campilobacter Jejuni
Cytomegalovirus
Epstain-Barr virus
Symptoms: symmetrical

ascending weakness, reduce reflexes, peripheral loss of sensation, neuropathic pain, facial nerve weakness

Слайд 5

GUILLAIN-BARRE
Diagnosis:
clinical
Brighton criteria
Nerve conduction studies (reduced signal)
Lumbar puncture (raised

protein)

Слайд 6

GUILLAIN-BARRE
Treatment:
IV immunoglobulins
Plasma exchange
Supportive care
VTE prophylaxis
Respiratory failure: intubation and ventilation; admission to

ICU

Слайд 7

CHARCOT-MARIE-TOOTH
Hereditary motor and sensory neuropathy of the peripheral nervous system
Signs and

symptoms:
Muscle wasting, cramps, spasm of the legs and arms
Loss of sensation of the lower and upper limbs

Слайд 8

CHARCOT-MARIE-TOOTH
Diagnosis:
Nerve conduction studies
Nerve biopsy (onion bulb)
DNA testing
Treatment: no cure
Occupation, physical therapy,

podiatrist, orthopedic surgery

Слайд 9

MYASTHENIA GRAVIS
Autoimmune disease affecting skeletal muscles
Affects young women and older men

Слайд 10

MYASTHENIA GRAVIS
Symptoms:
Weakness neck, face, arms
Eyelid drooping “Ptosis”
Appearance mask-like (very sleepy look)
Keep

choking/gagging when eating
No energy
Extraocular muscle involvement
Slurred speech
Shortness of breath

Neurology. Spinal cord compression

Содержание

MOTOR NEURON DISEASEInherited or sporadicConditions:Amyotrophic lateral sclerosis (Lou (Gehrig disease)Progressive bulbar

MOTOR NEURON DISEASESymptoms:Upper mor neuron: Increase muscle tone/stiffness – spastic paralysis,

GUILLAIN-BARREAcute paralytic polyneuropathyTriggered by infection : Campilobacter Jejuni CytomegalovirusEpstain-Barr virusSymptoms: symmetrical

GUILLAIN-BARREDiagnosis: clinical Brighton criteriaNerve conduction studies (reduced signal) Lumbar puncture (raised

GUILLAIN-BARRETreatment:IV immunoglobulinsPlasma exchangeSupportive careVTE prophylaxisRespiratory failure: intubation and ventilation; admission to

CHARCOT-MARIE-TOOTHHereditary motor and sensory neuropathy of the peripheral nervous systemSigns and

CHARCOT-MARIE-TOOTHDiagnosis:Nerve conduction studiesNerve biopsy (onion bulb)DNA testingTreatment: no cureOccupation, physical therapy,

MYASTHENIA GRAVISAutoimmune disease affecting skeletal musclesAffects young women and older men

MYASTHENIA GRAVISSymptoms:Weakness neck, face, armsEyelid drooping “Ptosis”Appearance mask-like (very sleepy look)Keep

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