Biological Beginnings - Prenatal Development

Содержание

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Handouts for this Chapter NY Times article- The Mysterious Tree of a Newborn’s Life

Handouts for this Chapter

NY Times article- The Mysterious Tree of a

Newborn’s Life
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The basis of human development All cells in the body have

The basis of human development

All cells in the body have 46

chromosomes, arranged in 23 pairs (except for the sperm and egg)
Mitosis- process in which cells reproduce, the
cell’s nucleus duplicates itself & the cell divides. Also, 2 new cells are formed with 23 pairs of chromosomes.
Meiosis- a cell from testes and a cell from the ovaries (egg and sperm-gametes) duplicate their chromosomes and then divide twice (4 cells are formed)
Fertilization- egg and sperm join to create a single cell (a zygote)
In the zygote- 23 unpaired chromosomes from egg and 23 from sperm combine to form one set of 23 paired chromosomes. So… each parent contributes half genetically to the offspring.
Google: Conception Picture Slideshow
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Dominant-Recessive genes Dominant gene- always exerts its effects/ it overrides the

Dominant-Recessive genes

Dominant gene- always exerts its effects/ it overrides the influence

of the other gene
Recessive gene- only exerts its influence if the two genes of a pair are recessive.
Ex: the recessive gene for blue eyes will show in offspring if both parents have that recessive gene (or are carriers)
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Prenatal development Conception- occurs when a single sperm cells fuses with

Prenatal development

Conception- occurs when a single sperm cells fuses with an

ovum (egg) in the fallopian tube. Also called fertilization.
3 main periods:
Germinal
Embryonic
Fetal
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Germinal period Takes place in first 2 weeks after conception Includes

Germinal period

Takes place in first 2 weeks after conception
Includes creation of

the zygote, cell division (mitosis), and attachment to the uterine wall
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Embryonic period Occurs from 2 to 8 weeks after conception Organs

Embryonic period

Occurs from 2 to 8 weeks after conception
Organs start to

appear
Mass of cells is now called an embryo
Three layers of cells form:
Endoderm- inner layer which become digestive and respiratory systems
Ectoderm- outermost which become the nervous syetm, skin parts
Mesoderm- middle layer which becomes bones, muscles, circulatory system, etc.
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Some Videos Inside Pregnancy https://www.youtube.com/results?search_query=inside+pregnancy+weeks+1+to+9&sm=1 https://www.youtube.com/watch?v=sivegxcp2Bk

Some Videos

Inside Pregnancy
https://www.youtube.com/results?search_query=inside+pregnancy+weeks+1+to+9&sm=1
https://www.youtube.com/watch?v=sivegxcp2Bk

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More on embryonic period Life support for embryo develops Three components:

More on embryonic period

Life support for embryo develops
Three components:
Amnion- contains clear

fluid in which embryo floats (shock proof)
Umbilical cord- contains two arteries and vein and connects baby to placenta
Placenta- group of tissues which pass along nutrients, oxygen, water to fetus.
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The fetal period 2 months to birth At 3 months, face,

The fetal period

2 months to birth
At 3 months, face, forehead, chin,

etc are distinguishable
By 5th month-mother can feel movement, can distinguish sex organs
By end of 7th month-fetus weighs approx 3 lbs and is considered viable.
During 8th and 9 month- fatty tissue develops, kidney, heart and lungs develop further.
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Trimesters Another way to divide prenatal development Germinal and embryonic period

Trimesters

Another way to divide prenatal development
Germinal and embryonic period occur during

the first trimester
Viability occurs at the beginning of third trimester
Developing baby is more susceptible to toxins during first trimester.
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Prenatal testing Ultrasound-noninvasive, rely on high frequency sound waves to detect

Prenatal testing

Ultrasound-noninvasive, rely on high frequency sound waves to detect heart

beat, transformed into a visual representation of inner structures (can detect structural abnormalities)
Amniocentesis- between 15th and 18th week of pregnancy, a sample of amniotic fluid is taken and tested for disorders (chromosome & metabolic)/ can bring 1 in 200 miscarraiges
Blood screening- during 16th-18th week, can detect spina bifida and down syndrome
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Infertility Can be due to the male or female Woman may

Infertility

Can be due to the male or female
Woman may not be

ovulating, may be producing damaged eggs, fallopian tube may be blocked
Men may produce too few sperm or they may have mobility issues
Hormone treatment could be helpful or IVF
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Hazards to prenatal development Prescription/ non prescription drugs Psychoactive drugs Incompatible

Hazards to prenatal development

Prescription/ non prescription drugs
Psychoactive drugs
Incompatible blood types
Maternal diseases
Maternal

poor nutrition
Maternal age
Envirnonmental factors
Paternal factors
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Teratogens Any agent that can cause a birth defect Three factors

Teratogens

Any agent that can cause a birth defect
Three factors related to

how damaging a teratogen can be:
Dose-the greater the dose, the more damage
Time of exposure-embryonic period is most vulnerable (when organs are being formed).
Genetic susceptibility- linked to genetic make up of mother and baby.
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Prescription/non prescription drugs Most harmful prescription are antibiotics, antidepressants, certain synthetic

Prescription/non prescription drugs

Most harmful prescription are antibiotics, antidepressants, certain synthetic hormones,

and Accutane
Most harmful non-prescription- aspirin and diet pills
Let’s watch Video on Thalidomide- http://www.nytimes.com/2013/09/23/booming/the-death-and-afterlife-of-thalidomide.html?action=click&module=Search®ion=searchResults%230&version=&url=http%3A%2F%2Fquery.nytimes.com%2Fsearch%2Fsitesearch%2F%3Faction%3Dclick%26region%3DMasthead%26pgtype%3DHomepage%26module%3DSearchSubmit%26contentCollection%3DHomepage%26t%3Dqry743%23%2Feffects+of+thalidomide&_r=1
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Psychoactive drugs Caffeine- risk of fetal death if more than two

Psychoactive drugs

Caffeine- risk of fetal death if more than two cups

per day
Alcohol- (FAS)
Nicotine- preterm births and low birth weight, SIDS
Cocaine- (reduced birth weight and length, higher excitability, slower reflexes, learning disabilities)
Marijuana- related to deficits in memory & information processing
Methamphetamine- (speeds up nervous system, high infant mortality)
Heroin- babies are born addicted, tremors, irritability
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Maternal Diet Obesity can cause still births Malnourishment can lead to

Maternal Diet

Obesity can cause still births
Malnourishment can lead to malformation of

fetus
Lack of folic acid-can be related to spina bifida
Eating fish (ex; sushi)-can have toxins, mercury which easily goes across the placenta and can lead to nervous system problems
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Maternal age Adolescent mothers and over age 35 are at risk

Maternal age

Adolescent mothers and over age 35 are at risk
Higher mortality

rate from teenage mothers-due to immaturity of reproductive system, own health care and education.
Women over age 35-run risk of down syndrome child
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Stages of Birth Occurs in three stages: Uterine contractions are 15-20

Stages of Birth

Occurs in three stages:
Uterine contractions are 15-20 minutes, cervix

begins to open. (longest stage)
baby starts to enter the birth canal, contractions are more rapid and intense,
Afterbirth- placenta, umbillical cord are detached.
Let’s watch A Walk to the Beautiful- PBS NOVA documentaryhttp://www.pbs.org/wgbh/nova/body/a-walk-to-beautiful.html
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Methods of childbirth Medication Natural Cesarean a. medical procedure done in

Methods of childbirth

Medication
Natural
Cesarean
a. medical procedure done in higher risk situations.
b.

baby is breech (buttocks are first to emerge)
C. when baby’s head is too large, baby is lying crossways
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Apgar scale Used to assess the health of newborns at one

Apgar scale

Used to assess the health of newborns at one and

five minutes after birth.
Evaluates things such as the following: breathing effort, heart rate, body color
Newborns are given a score for each area (either a 0,1, or 2)
It identifies high risk infants
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Infants at risk Low birth weight- These infants weight less than

Infants at risk

Low birth weight- These infants weight less than 5.5

lbs.- poverty, drug use can cause this.
Preterm infants- those born three weeks or more before pregnancy reached full term (38 weeks typically full term), can be due to increased maternal age, increased stress, mother’s illness, etc.