Содержание
- 2. DNA
- 3. Deoxyribonucleic acid DNA - a polymer of deoxyribo-nucleotides. Usually double stranded. And have double-helix structure. found
- 4. DNA as an acidic substance present in nucleus was first identified by Friedrich Meischer in 1868.
- 5. In 1953 , James Watson and Francis Crick, described a very simple but famous Double Helix
- 6. FRANCIS CRICK AND JAMES WATSON
- 7. The scientific framework for their breakthrough was provided by other scientists including Linus Pauling Rosalind Franklin
- 8. She worked in same laboratory as Maurice Wilkins. She study X-ray diffraction to study wet fibers
- 9. She made marked advances in X-ray diffraction techniques with DNA The diffraction pattern she obtained suggested
- 10. Rosalind Franklin Maurice Wilkins
- 11. DNA Structure DNA has three main components 1. Deoxyribose (a pentose sugar) 2. Base (there are
- 12. H H OH O CH2 Base Phosphate Ribose OH 5′ 4′ 1′ 3′ 2′ O O
- 13. The Nitrogenous Bases THEY ARE DIVIDED INTO TWO GROUPS Pyrimidines and purines PYRIMIDINES (MADE OF ONE
- 14. Nitrogenous bases of DNA & RNA
- 15. Nucleotide Structure Nucleotides are formed by the condensation of a sugar, phosphate and one of the
- 16. H H H O CH2 Base DNA nucleotide Phosphate Deoxyribose 5′ OH 4′ 1′ 3′ 2′
- 17. Base + sugar ? nucleoside Example Adenine + ribose = Adenosine Adenine + deoxyribose = Deoxyadenosine
- 18. Base always attached here Deoxyadenosine Deoxyadenosine monophosphate Doxyadenosine diphosphate Adenine Phosphate groups Phosphoester bond Deoxyribose H
- 19. Nucleotides are linked together by covalent bonds called phosphodiester linkage. 1 2 3 4 5 1
- 20. NH2 N O N O N O N Adenine (A) Guanine (G) Thymine (T) Bases Backbone
- 21. DNA Double Helix & Hydrogen bonding Salient features of the Double-helix structure of DNA: It is
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