Skin cancer. Melanoma

Содержание

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UV radiation increase risk of skin cancer on 70%

UV radiation increase risk of skin cancer on 70%

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Common Premalignant and Malignant Neoplasms of the Skin

Common Premalignant and Malignant Neoplasms of the Skin

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Obligate precancerous Pigment kseroderma, Bowen disease, Eritroplasia Keyra

Obligate precancerous Pigment kseroderma, Bowen disease, Eritroplasia Keyra

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Facultative precancerous Keratoacantoma of nose, Diskeratosis in old man, seborrhea keratosis, skin horn

Facultative precancerous Keratoacantoma of nose, Diskeratosis in old man, seborrhea keratosis,

skin horn
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Basal cell carcinoma is a malignant tumor that rarely metastasizes. It

Basal cell carcinoma is a malignant tumor that rarely metastasizes. It is composed

of cells that arise from the epidermis and the appendages which resemble the basal layer of the epidermis and is associated with a characteristic stroma. It tends to grow slowly and invade locally over many years, which eventually leads to ulceration, hence the name “rodent ulcer.”

BASAL CELL CARCINOMA Definition

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Basal cell carcinomas account for more than 75% of keratinocytic skin

Basal cell carcinomas account for more than 75% of keratinocytic skin cancers diagnosed

in the United States each year. The incidence of basal cell carcinoma varies from 422 per 100,000 general population in Kauai, Hawaii, to 146 per 100,000 in Rochester, Minnesota. The average annual incidence in the United States is 191 per 100,000 white persons. It is the most common form of skin cancer in whites. It is very rare in darkly pigmented people. It most frequently occurs in persons older than 40 years of age. The frequency is slightly higher in males. Other risk factors include geographic locations with high solar intensity, exposures to inorganic trivalent arsenic, ionizing radiation, and immunosuppression.

Epidemiology

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Basal cell carcinoma

Basal cell carcinoma

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Basal cell carcinoma (pigment form)

Basal cell carcinoma (pigment form)

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Ulcerous type (ulcus rоdеns) (Basalioma terebrans)

Ulcerous type

(ulcus rоdеns)

(Basalioma terebrans)

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Perforating basalioma

Perforating basalioma

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Cryosurgery

Cryosurgery

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Basal cell carcinoma before and after cryosurgery

Basal cell carcinoma before and after cryosurgery

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Squamous cell carcinoma is a malignant tumor arising from epidermal or

Squamous cell carcinoma is a malignant tumor arising from epidermal or appendageal

keratinocytes or from the squamous mucosal epithelium. There is often a history of damage by exogenous agents acting as carcinogens, such as sunlight, ionizing radiation, local irritants, or arsenic ingestion. The tumor cells have a tendency toward keratin formation.

SQUAMOUS CELL CARCINOMA. Definition

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Ways of lymphatic spread

Ways of lymphatic spread

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Cancer of skin

Cancer of skin

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Cancer of skin (exophyt form)

Cancer of skin (exophyt form)

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Cancer of skin. Advanced form

Cancer of skin. Advanced form

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Malignant melanoma of skin accounts for 160,000 new cases annually, with

Malignant melanoma of skin accounts for 160,000 new cases annually, with slightly

more occurring in women than in men (M:F sex ratio, 0.97). It is a tumor particularly common in White populations living in sunny climates. High rates of incidence are found in Australia/New Zealand, North America, and northern Europe

Epidemiology

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Melanoma

Melanoma

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Epidemiology

Epidemiology

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Dangerous nevus Nevus of Settona, Intradermal nevus, Blue nevus

Dangerous nevus Nevus of Settona, Intradermal nevus, Blue nevus

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Dangerous nevus gigantic nevus, Oto’s nevus, Ito’s nevus

Dangerous nevus gigantic nevus, Oto’s nevus, Ito’s nevus

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Dangerous nevus Melanoz of Dubrea

Dangerous nevus Melanoz of Dubrea

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Melanoma

Melanoma

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Differential Clinical Features of the Common Types of Melanoma

Differential Clinical Features of the Common Types of Melanoma

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Clark’s method of microstaging defines five levels of penetration through the dermis to the subcutaneous fat

Clark’s method of microstaging defines five levels of penetration through the dermis to

the subcutaneous fat