Содержание

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PART 1 Anatomy of the heart

PART 1

Anatomy of the heart

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Cardiac arrest Checking airway, breathing and circulation 1) Start CPR 30

Cardiac arrest

Checking airway, breathing and circulation
1) Start CPR
30 compression: 2 breath
Minimize

interruption
2) Attach defibrillator/Monitor
3) Assess rhythm
Shockable: ventricular tachycardia or ventricular fibrillation
Non-shockable: asystole

Shockable: first provide shock, then CPR for 2 min
No shock: CPR (cardiopulmonary resuscitation) for 2 min, after one cycle provide adrenaline 1mg immediately
Questions:
What is the step that given the best long term outcome? Defibrillation
Best for neurologic recovery after cardiac arrest? To induce hypothermia

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PART 2 Electrically conductive disorders

PART 2

Electrically conductive disorders

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Supraventricular tachycardia Narrow QRS complex HR >140bpm Unusual P waves

Supraventricular tachycardia

Narrow QRS complex
HR >140bpm
Unusual P waves

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Supraventricular tachycardia Management: For unstable patients: synchronized cardioversion BP below 90/60

Supraventricular tachycardia

Management:
For unstable patients: synchronized cardioversion
BP below 90/60 or

in syncope
For stable patients: vagal manoeuvres, carotid sinus massage

Adenosine
Calcium channel blockers (Verapamil, Diltiazem)
Beta blockers (Metoprolol, Propranolol)
Digoxin

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Atrial fibrillation Absent P waves V1,V2,V3, avF Irregular rhythm

Atrial fibrillation

Absent P waves
V1,V2,V3, avF
Irregular rhythm

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Atrial fibrillation Management: For unstable patients: synchronized cardioversion For stable patients:

Atrial fibrillation

Management:
For unstable patients: synchronized cardioversion
For stable patients:
Beta blockers (Metoprolol)
Diltiazem
Verapamil
Digoxin

To

prevent stroke for patients with rick factors
Warfarin
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Atrial flutter Management For unstable patients: synchronized cardioversion For stable: rate control + warfarin

Atrial flutter

Management
For unstable patients: synchronized cardioversion
For stable: rate control + warfarin

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Premature ventricular beat Causes: post myocardial infarction, hypokalemia Symptoms: Dyspnea Multiple/multifocal

Premature ventricular beat

Causes: post myocardial infarction, hypokalemia
Symptoms:
Dyspnea
Multiple/multifocal ectopic beats
Management
If no

symptoms and no multiple premature beats: no need for treatment
With symptoms: beta blockers (metoprolol, betoxolol, esmolol)
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Ventricular tachycardia Tachycardia Wide QRS Regular rhythm Management: Unstable + Pulseless:

Ventricular tachycardia

Tachycardia
Wide QRS
Regular rhythm
Management:
Unstable + Pulseless: unsynchronized cardioversion - defibrillator
Unstable +

Pulse: synchronized cardioversion
Stable: amiodarone, procainamide
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Ventricular fibrillation Zigzag pattern Managment

Ventricular fibrillation

Zigzag pattern
Managment

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Bradycardia Causes: Sinus node dysfunction Conduction blocks The rhythm with a

Bradycardia

Causes:
Sinus node dysfunction
Conduction blocks
The rhythm with a rate of 50

bpm
If there are symptoms (faint, shortness of breath , lightheadedness, chest pain):
Atropine: 0.5mg every 3-5 min up to 3mg + adrenaline
Cardiac pacing
If no symptoms: no treatment needed
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Wolff Parkinson-white syndrome Short PR interval Wide QRS Delta wave Management

Wolff Parkinson-white syndrome

Short PR interval <12 sec
Wide QRS
Delta wave
Management
Unstable patient: cardioversion
Stable:

Amiodarone, Procainamide, Esmolol
WPW+SVT: Adenosine
WPW+AF: Amiodarone, Procainamide
Best treatment: Catheter ablation
Newer prescribe: digoxin and verapamile
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Torsades De Pointes Twisting of the QRS complex around the isoelectric

Torsades De Pointes

Twisting of the QRS complex around the isoelectric line
No

P wave
Irregular regular
Slow-fast-slow heart rhythm
Most common cause: alcohol, erythromycin
Unstable patient: defibrillator
Stable: MgSO4, amioddarone
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Heart block First degree: PR interval is more than 0.2 sec

Heart block

First degree: PR interval is more than 0.2 sec
No treatment

needed
Second degree
Mobitz type I
PR intervals gradually elongate until a P-wave is completely blocked
Mobitz type II
PR intervals are consistent but some P-waves don’t conduct
2:1 block
Treatment: pace maker

Third degree with junctional escape
Atria and ventricles beat separately
Ascent A wave in JVP
May have a completely loss of ventricular activity
Treatment: Pace maker

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Heart block

Heart block

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Hyperkalemia K+ nomal level 3.5-5.5 If there is ECG changes give

Hyperkalemia

K+ nomal level 3.5-5.5
If there is ECG changes give IV calcium

gluconate
If no changes: insulin+glucose
K+ level >7 prescribe IV calcium gluconate

Tall, peaked T waves with narrow base
Shortened QT interval
ST-segment depression
Drugs
ACE inhibitors, Amiloride, ARB, Beta blockers, NSAIDs, Heparin, Spironolactone, Loop diuretics

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Hypokalemia

Hypokalemia

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LBBB M shaped comlex usually in leads in V% and V6

LBBB

M shaped comlex usually in leads in V% and V6

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LBBB

LBBB

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Right Bundle branch block M shapes complex in leads usually in

Right Bundle branch block

M shapes complex in leads usually in V1

and V2
Usually associated with ASD
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Pericarditis Caused by Viral coxsackie virus Diffuse ST segment elevation Treatment:

Pericarditis

Caused by Viral coxsackie virus
Diffuse ST segment elevation
Treatment: NSAIDs

Symptoms of pericarditis
Chest

pain increased by movement and respiration
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Hypertrophic obstructive cardiomyopathy Clinical features Sudden loss of consciousness while on

Hypertrophic obstructive cardiomyopathy

Clinical features Sudden loss of consciousness while on exertion,

family history, young age
Causes of sudden death: arrhythmia, obstruction
Diagnosis: Systolic murmur over sternal border, if Echo is normal -> Stress Echo
Treatment: beta blockers, CCB, implantable defibrillator, heart transplantation
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PART 3

PART 3

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Abdominal aorta aneurysm Clinical features: A bulge or swelling in the

Abdominal aorta aneurysm

Clinical features:
A bulge or swelling in the aorta
Family history
May

be asymptomatic, abdominal discomfort, pulsatile mass
Normal 10-30mm
Emergency situation >30 mm

Treatment
Dacron graft after 5 years of AAA
Endovascular graft
Rupture of AAA: abdominal pain+ pale+ shocked +/- back pain

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Aortic dissection Symptoms: severe, sudden, midline tearing or rippig sensation Occlusion

Aortic dissection

Symptoms: severe, sudden, midline tearing or rippig sensation
Occlusion of the

coronary or kidney arteries
Diagnosis: X-ray and CT scan
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Superior vena cava syndrome Caused by: external compression or thrombosis Malignant

Superior vena cava syndrome

Caused by: external compression or thrombosis
Malignant mediastinal tumour
Bronchogenic

carcinoma
Non-Hodgkin lymphoma
Mediastinal fibrosis
Vascular diseases
Infections
Teratoma, cystic hygroma
Pericarditis, atrial myxoma
Thrombosis due to central vein catheter

Clinical features: dyspnoea, facial swelling, head fullness, cough, arm swelling, chest pain, dysphagia, orthopnea, distorted vision, hoarseness, stridor, pleural effusion

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Superior vena cava syndrome Signs Distended venous distention of the neck

Superior vena cava syndrome

Signs
Distended venous distention of the neck and chest

wall
Facial oedema
Upper extremity oedema
Mental status changes
Plethoa
Cyanosis
Stupor
Coma
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Superior vena cava syndrome

Superior vena cava syndrome

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Hypertension Causes: Esential Secondary Kidney (glomerulonephritis, kidney artery stenosis) Endocrine (primary

Hypertension

Causes:
Esential
Secondary
Kidney (glomerulonephritis, kidney artery stenosis)
Endocrine (primary aldosteronism, Cushing syndrome, pheochromocytoma)
Coarctation of

the aorta
Immune disorder
Drugs (NSAIDs, Corticosteroids)
Pregnancy
Paroxysmal hypertension
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Hypertension Diagnosis: ambulatory 24 hours monitoring Management: Diet, exercises, weight control

Hypertension

Diagnosis: ambulatory 24 hours monitoring

Management:
Diet, exercises, weight control
ACE inhibitors (-pril: Captopril,

Lisinopril, Enalapril) or ARB
ACEI, ARB and diuretic
Beta blocker
Foe elderly: thiazides, Indapamide
(Amiodipine)
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Dilated Cardiomyopathy Most common causes: Alcohol, Coxsackie virus, drugs (doxorubicin, anthracycline)

Dilated Cardiomyopathy

Most common causes:
Alcohol, Coxsackie virus, drugs (doxorubicin, anthracycline)
Clinical features:
Pedal

oedema
Orthopnea
Dyspnea
Arrhythmia

Diagnosis: Echo, x-ray
Management: ACEI and BB

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PART 4

PART 4

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Mitral Stenosis Clinical features: murmur(mid-diastolic with presystolic accentuation) loud S1 The

Mitral Stenosis

Clinical features:
murmur(mid-diastolic with presystolic accentuation)
loud S1
The character is

rumbling
Site is on the apex
It doesn’t radiate to any other position
MS has an opening snap (affects the left atrium)
Fatigue, SOB, exercise intolerance, cough, palpitations

Diagnosis: echo (left atrial enlargement)
Management:
Ballooning
Surgery: when valve area is less then 1 cm
Mitral valve repair
Mitral valve replacement

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Mitral Regurgitation The most common cause: mitral valve prolapse Clinical features:

Mitral Regurgitation

The most common cause: mitral valve prolapse
Clinical features:
History of

Rheumatic fever
Murmur
Pan-systolic over the apex and radiates to the axilla
Acute: pulmonary edema, congestive heart failure
Chronic: fatigue, pulmonary congestion/edema

Diagnosis: echo (left atrial enlargement)
Treatment:
Diuretics, BB
Surgery : repair or replacement

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Mitral valve prolapse Clinical features: Young females (with familial connection) Atypical

Mitral valve prolapse

Clinical features:
Young females (with familial connection)
Atypical chest pain
Palpitations
Hyperventilation
Migranes


A mid-systolic click – late systolic murmur
Causes: idiopathic, Marfan Syndrome, Ehlers Danlos Syndrome

Diagnosis: echo
Treatment: BB
Complication: progression to mitral regurgitation, certain arrhythmias, infective endocarditis, thromboembolism

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Aortic stenosis Clinical features: Chest pain Syncope SOB Sudden death Loss

Aortic stenosis

Clinical features:
Chest pain
Syncope
SOB
Sudden death
Loss of consciousness
Microangiopathic hemolytic anemia
Small or weak

pulse
Yang patients: bicuspid aortic valve; rheumatic fever
Elder: calcific aortic valve

Murmur:
Systolic murmur over right 2nd intercostal space, radiating to carotid
Increased by leaning forward
Crescendo-decrescendo murmur
Diagnosis: Echo (left ventricular hypertrophy)
Treatment:
Valvuloplasty by balloon
Valve replacement surgery
When: patient has severe symptoms, the pressure gradient is more then 50 mmHg, valve area less then 0.8cm

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Aortic regurgitation Causes by: 80% idiopatic Marfan Syndrome Rheumatic fever Murmur:

Aortic regurgitation

Causes by:
80% idiopatic
Marfan Syndrome
Rheumatic fever
Murmur:
Early diastolic decrescendo over left

2nd intercostal space radiating to the apex S2;
Wide fixed
Murmur is increased by leaning forward

Clinical features: fatigue, syncope, SOB, palpitations, widened pulse pressure
Diagnosis: echo (left ventricular dilatation)
Treatment: replace valve
AR is associated with: RBBB, atrial septal defect

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Constrictive pericarditis Causes: Tb, autoimmune disorders Clinical features: Systemic congestion Paradoxical

Constrictive pericarditis

Causes: Tb, autoimmune disorders
Clinical features:
Systemic congestion
Paradoxical increase in JVP distention

and pressure during inspiration (Kussmaul sigh)
Congested Pulsated neck veins
Pulsus paradoxus

Diagnosis: CT
Treatment: Pericardiectomy, Pericardiocentesis
Complications:
Cardiac tamponade
Becks triad: hypotension, increased JVP, decreased heart sound

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Infective Endocarditis Infection of the cardiac valves or endometrium Clinical feature:

Infective Endocarditis

Infection of the cardiac valves or endometrium
Clinical feature:
Fever of unknown

region
Cardiac murmur
Embolism

Risk factors: known heart disease, history of endocarditis, abnormal valves, mitral valve prolapse, calcified aortic valve, congenital cardiac defects (VSD, PDA)
Classical tetrad:
Sighs of infection
Signs of heart disease
Signs of embolism
Immunological phenomenon

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Infective Endocarditis Symptoms: Osler nodes Janeway lesons Splenomegaly Petechiae Roth spots Cardiac Murmurs Splinter hemorrhages Clubbing

Infective Endocarditis

Symptoms:
Osler nodes
Janeway lesons
Splenomegaly
Petechiae
Roth spots
Cardiac Murmurs
Splinter hemorrhages
Clubbing

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Infective Endocarditis Diagnosis: ERS increase, anemia and leucocytosis In urine: proteinuria

Infective Endocarditis

Diagnosis:
ERS increase, anemia and leucocytosis
In urine: proteinuria and hematuria
Blood

culture
Transesophageal echocardiography (to visualize vegetations)
Treatment: Benzylpenicillin, Flucloxacillin, gentamicin, vancomycin
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Myocardial infarction Criteria of MI: History of prolonged ischemic pain Typical

Myocardial infarction

Criteria of MI:
History of prolonged ischemic pain
Typical ECG appearance
Rise and

fall of cardiac enzymes
Causes:
Thrombosis with occlusion
Haemorrhage under a plaque
Rupture of a plaque
Coronary artery spasm

Investigation:
ECG: ST segment elevation greater than 1 mm in two contagious leads in the presence of symptoms and development of new left bundle branch block
Cardial Enzymes
Troponin I or T (start rising 3-12 hrs and reached peak at 24 hours and persist for about 5-14 days)
Creatine Kinase (it peaks at 20-24 hrs and usually returns to normal after 48hrs)
Coronary angiogram

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Myocardial infarction Management: Provide ABC (Airway, breathing, compression) Aspirin BB and

Myocardial infarction

Management:
Provide ABC (Airway, breathing, compression)
Aspirin
BB and ACE inhibitors
Coronary angioplasty
Nitrates
Anticoagulants (warfarin,

heparin)
Statins
STEMI + 2 hours from onset -> thrombolysis
Percutaneous coronary intervention
Coronary artery Bypass Graff
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Rheumatic fever Clinical features: Young people 5-15 Acute onset fever, joint

Rheumatic fever

Clinical features:
Young people 5-15
Acute onset fever, joint pain, malaise
Fitting arthralgia

mainly in legs (knees, ankles) and arms (elbow and wrist)
May appear with a sore throat

Diagnosis: FBC (Full blood count), throat swab, ESR, Streptococcal ASOT, Streptococcal anti-Dnase B (repeat in 10-14 days), C-reactive protein, ECG and echocardiogram
Treatment:
Rest in bed until CRP is normal for 2 weeks
Benzathine Penicillin 900mg IM
Statim or Phenoxymethylpenicillin
Paracetamol, aspirin, Naproxen (arthritis
Diuretics (carditis)
Prophylactic long term penicillin

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Rheumatic fever erythema marginatum

Rheumatic fever erythema marginatum

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