Virus infections as risk factors in the development of bronchopulmonary dysplasia (BPD)

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Bronchopulmonary dysplasia (Chronic neonatal lung disease) https://www.mountnittany.org/articles/healthsheets/587 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530566/

Bronchopulmonary dysplasia (Chronic neonatal lung disease)

https://www.mountnittany.org/articles/healthsheets/587
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530566/

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Aim By usage of the new in vitro and in vivo

Aim

By usage of the new in vitro and in vivo models

to investigate how viral infections may determine the development of BPD in short and long-term studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530566

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Hypothesis 1. There is an effect of viral infection on the

Hypothesis

1. There is an effect of viral infection on the development

of BPD.
2. The mechanism of the effect could be established.
3. New targets for interference with the disease might be found.
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Viral infection https://www.helmholtz-muenchen.de/agv/forschung/arbeitsgruppen/research-group-models-of-infection/projects/index.html Murine gamma-herpesvirus 68 MHV-68 induces progressive pulmonary fibrosis

Viral infection

https://www.helmholtz-muenchen.de/agv/forschung/arbeitsgruppen/research-group-models-of-infection/projects/index.html

Murine gamma-herpesvirus 68
MHV-68 induces progressive
pulmonary fibrosis
Readily infects laboratory
mice
Perfect to

study chronic lung
disease in the mive model
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Experimental design

Experimental design

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Experimental design

Experimental design

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Discussion

Discussion

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Discussion

Discussion

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Cooperation project

Cooperation project