Virus infections as risk factors in the development of bronchopulmonary dysplasia (BPD)

Сентябрь 12, 2022

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Virus infections as risk factors in the development of bronchopulmonary dysplasia (BPD)

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2. Bronchopulmonary dysplasia (Chronic neonatal lung disease) https://www.mountnittany.org/articles/healthsheets/587 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530566/
3. Aim By usage new in vitro and in vivo models to investigate how viral infections may
4. Hypothesis 1. There is an effect of viral infection MHV-68 on the development of BPD. 2.
5. MHV-68 https://www.helmholtz-muenchen.de/agv/forschung/arbeitsgruppen/research-group-models-of-infection/projects/index.html Murine gamma-herpesvirus 68 The natural route of infection has been argued that spread is
6. Experimental design
7. Experimental design
8. Discussion
9. Research Unit Lung Repair and Regeneration (LRR) Comprehensive Pneumology Center (CPC) Helmholtz-Zentrum München Supervisor: Prof. Dr.
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Bronchopulmonary dysplasia (Chronic neonatal lung disease)
https://www.mountnittany.org/articles/healthsheets/587
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530566/

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Aim
By usage new in vitro and in vivo models to investigate

how viral infections may determine the development of BPD in short and long-term studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530566

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Hypothesis
1. There is an effect of viral infection MHV-68 on the

development of BPD.
2. The mechanism of the effect could be established.
3. New targets for interference with the disease are able to be found.

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MHV-68
https://www.helmholtz-muenchen.de/agv/forschung/arbeitsgruppen/research-group-models-of-infection/projects/index.html
Murine gamma-herpesvirus 68
The natural route of infection
has been argued that

spread is
likely through the respiratory
route
There is an acute phase of virus
replication in lungs
The infection in the settings of
immune responce is associated
with the development of
lymphomas

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Experimental design

Слайд 7

Experimental design

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Discussion

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Research Unit Lung Repair and Regeneration (LRR)
Comprehensive Pneumology Center (CPC)
Helmholtz-Zentrum München
Supervisor:

Prof. Dr. Heiko Adler
Thesis committee:
Prof. Dr. Heiko Adler
PD Dr. Barbara Adler
PD Dr. Anne Hilgendorff