Содержание
- 2. Retrosynthetic analysis of paclitaxel (1)
- 3. Synthesis of the C Ring of Paclitaxel
- 4. Preparation of the A−C Rings of Paclitaxel
- 5. Preparation of the ABC Precursor 4
- 6. Construction of ABC Ring of Paclitaxel 3
- 7. 2. Construction of the ABCD Ring and Formal Synthesis
- 8. Synthetic plan for paclitaxel (1) from ABC ring (3)
- 9. Construction of a Bridgehead Olefin by Chugaev Reaction 9
- 10. Synthesis of Taxoid 4
- 11. Synthesis of Takahashi’s Oxetane Intermediate
- 12. 3. Total synthesis of Taxol (baccatinIII) by Takashi
- 13. Abbreviation Thexylborane TBDPSCl tBuPh2SiCl TPAP Pr4NRuO4 NMO MS4A мол.сита 4A 3,5-DMP L-selectride EDCl TBHP
- 15. Luche reduction mechanism
- 16. Chugaev reaction mechanism
- 18. Скачать презентацию